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DeCS
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Descriptor English:
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Selective Estrogen Receptor Modulators
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Descriptor Spanish:
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Moduladores Selectivos de los Receptores de Estrógeno
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Descriptor Portuguese:
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Moduladores Seletivos de Receptor Estrogênico
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Synonyms English:
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Estrogen Receptor Modulator, Selective
Estrogen Receptor Modulators, Selective
SERM
SERMs
Selective Estrogen Receptor Modulator
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Tree Number:
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D06.347.360.827
D27.505.696.399.450.360.827
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Definition English:
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A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63) |
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Indexing Annotation English:
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do not confuse with ESTROGEN RECEPTOR MODULATORS
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See Related English:
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Bone Density Conservation Agents
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History Note English:
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2000
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Allowable Qualifiers English:
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Record Number:
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34403
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Unique Identifier:
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D020845
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Occurrence in VHL:
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Similar:
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DeCS
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