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REZULIN
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DeCS
Descriptor
English
:
Troglitazone
Descriptor
Spanish
:
Troglitazona
Descriptor
Portuguese
:
Troglitazona
Synonyms
English
:
5-(4-((6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl-methoxy)benzyl)-2,4-thiazolidinedione) - T
CS 045
CS-045
CS045
Prelay
Rezulin
Tree Number:
D02.886.675.933.750
D03.383.129.708.933.750
D03.383.663.283.240.612
D03.633.100.150.240.612
Definition
English
:
A chroman and thiazolidinedione derivative that acts as a
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS
(PPAR) agonist. It was formerly used in the treatment of TYPE 2
DIABETES MELLITUS
, but has been withdrawn due to hepatotoxicity.
Pharmacological Action:
Hypoglycemic Agents
History Note
English
:
2019 (1988)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
57589
Unique Identifier:
D000077288
Occurrence in VHL
:
Similar:
DeCS