Search on: RENIN 
Descriptors Found: 1
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Descriptor English:   Renin 
Descriptor Spanish:   Renina 
Descriptor Portuguese:   Renina 
Synonyms English:   Angiotensin Forming Enzyme
Angiotensin-Forming Enzyme
Angiotensinogenase
Big Renin
Cryorenin
Inactive Renin
Pre Prorenin
Pre-Prorenin
Preprorenin
Prorenin
Renin, Big
Renin, Inactive  
Tree Number:   D08.811.277.656.074.500.780
D08.811.277.656.300.048.780
D08.811.277.656.837.750
Definition English:   A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19. 
Indexing Annotation English:   do not confuse with RENNIN see CHYMOSIN
History Note English:   1963; for PRORENIN use RENIN (NM) 1977-2003, for PREPRORENIN use RENIN (NM) 1980-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   29553 
Unique Identifier:   D012083 

Occurrence in VHL:
 

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