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RALOXIFENE
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DeCS
Descriptor
English
:
Raloxifene Hydrochloride
Descriptor
Spanish
:
Clorhidrato de Raloxifeno
Descriptor
Portuguese
:
Cloridrato de Raloxifeno
Synonyms
English
:
Evista
Keoxifene
Keoxifene Hydrochloride
LY 139481
LY 156758
LY-139481
LY-156758
LY139481
LY156758
Raloxifene
Raloxifene HCl
Tree Number:
D02.455.426.559.389.150.700.900.775
Definition
English
:
A second generation selective estrogen receptor modulator (SERM) used to prevent
osteoporosis
in postmenopausal women. It has estrogen agonist effects on bone and
cholesterol
metabolism
but behaves as a complete estrogen antagonist on mammary gland and uterine
tissue.
Pharmacological Action:
Estrogen Antagonists
Selective Estrogen Receptor Modulators
Bone Density Conservation Agents
History Note
English
:
2000; use RALOXIFENE (NM) 1983-1999
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
34394
Unique Identifier:
D020849
Occurrence in VHL
:
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DeCS