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RG7204
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DeCS
Descriptor
English
:
Vemurafenib
Descriptor
Spanish
:
Vemurafenib
Descriptor
Portuguese
:
Vemurafenib
Synonyms
English
:
PLX 4032
PLX4032
R05185426
RG 7204
RG-7204
RG7204
Zelboraf
Tree Number:
D02.065.884.919
D02.886.590.700.919
D03.633.100.473.936
Definition
English
:
An indole sulfonamide compound and inhibitor of BRAF KINASES that is used for the treatment of unresectable or metastatic
MELANOMA.
Pharmacological Action:
Antineoplastic Agents
Protein Kinase Inhibitors
History Note
English
:
2019 (2010)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
57657
Unique Identifier:
D000077484
Occurrence in VHL
:
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DeCS