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R-51211
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DeCS
Descriptor
English
:
Itraconazole
Descriptor
Spanish
:
Itraconazol
Descriptor
Portuguese
:
Itraconazol
Synonyms
English
:
Orungal
R 51211
R-51211
R51211
Sporanox
Tree Number:
D03.383.129.799.550
D03.383.606.530
Definition
English
:
A triazole antifungal agent that inhibits
cytochrome
P-450-dependent
enzymes
required for
ERGOSTEROL
synthesis.
Pharmacological Action:
Antifungal Agents
14-alpha Demethylase Inhibitors
Cytochrome P-450 CYP3A Inhibitors
History Note
English
:
94; was ITRACONAZOLE (NM) 1984-93
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
31378
Unique Identifier:
D017964
Occurrence in VHL
:
Similar:
DeCS