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Descriptor English:   Carvedilol 
Descriptor Spanish:   Carvedilol 
Descriptor Portuguese:   Carvedilol 
Synonyms English:   14C-labeled Carvedilol
BM 14190
BM-14190
BM14190
Carvedilol Hydrochloride
Carvedilol, (+)
Carvedilol, (+)-isomer
Carvedilol, (+-)-isomer
Carvedilol, (-)
Carvedilol, (-)-isomer
Carvedilol, (R)-isomer
Carvedilol, (S)-isomer
Carvedilol, 14C labeled
Carvedilol, 14C-labeled
Coreg
Coropres
Dilatrend
Eucardic
Kredex
Querto  
Tree Number:   D02.033.100.624.151
D02.033.755.624.151
D02.092.063.624.151
D03.633.100.473.144.125
D03.633.300.148.125
Definition English:   A carbazole and propanol derivative that acts as a non-cardioselective beta blocker and vasodilator. It has blocking activity for ALPHA 1 ADRENERGIC RECEPTORS and, at higher doses, may function as a blocker of CALCIUM CHANNELS; it also has antioxidant properties. Carvedilol is used in the treatment of HYPERTENSION; ANGINA PECTORIS; and HEART FAILURE. It can also reduce the risk of death following MYOCARDIAL INFARCTION. 
Pharmacological Action:   Adrenergic beta-Antagonists
Antihypertensive Agents
Antioxidants
Calcium Channel Blockers
Vasodilator Agents
Adrenergic alpha-1 Receptor Antagonists
 
History Note English:   2019 (1984) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   57565 
Unique Identifier:   D000077261 

Occurrence in VHL: 		 

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