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PROGLUCAGON
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DeCS
Descriptor
English
:
Proglucagon
Descriptor
Spanish
:
Proglucagón
Descriptor
Portuguese
:
Proglucagon
Synonyms
English
:
Glucagon Precursor
Glucagon Precursors
Pre-Proglucagons
Preproglucagon
Preproglucagons
Pro Glucagon
Pro-Glucagon
Tree Number:
D06.472.317.680
D06.472.699.587.730
D12.644.548.586.730
D12.776.811.700
Definition
English
:
The common precursor polypeptide of pancreatic
GLUCAGON
and intestinal
GLUCAGON-LIKE PEPTIDES
.
Proglucagon
is the 158-amino acid segment of preproglucagon without the N-terminal signal sequence.
Proglucagon
is expressed in the
PANCREAS
;
INTESTINES
; and the
CENTRAL NERVOUS SYSTEM
. Posttranslational processing of
proglucagon
is tissue-specific yielding numerous bioactive
peptides.
History Note
English
:
2007 (2006); for GLUCAGON PRECURSOR use GLUCAGON PRECURSOR (NM) 1977-2007
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50566
Unique Identifier:
D052336
Occurrence in VHL
:
Similar:
DeCS