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PODOPHYLLIN
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DeCS
Descriptor
English
:
Podophyllin
Descriptor
Spanish
:
Podofilino
Descriptor
Portuguese
:
Podofilina
Synonyms
English
:
Podophyllum Resin
Resin, Podophyllum
Tree Number:
D20.215.784.500.675
Definition
English
:
Caustic extract from the roots of
Podophyllum peltatum
and P. emodi. It contains
PODOPHYLLOTOXIN
and its congeners and is very irritating to mucous
membranes
and skin.
Podophyllin
is a violent purgative that may cause CNS damage and
teratogenesis
. It is used as a paint for warts,
skin neoplasms
, and senile keratoses.
Pharmacological Action:
Antineoplastic Agents, Phytogenic
Caustics
Keratolytic Agents
History Note
English
:
72(64); was see under PODOPHYLLUM 1963-71
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
11463
Unique Identifier:
D011033
Occurrence in VHL
:
Similar:
DeCS