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PINACIDIL
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DeCS
Descriptor
English
:
Pinacidil
Descriptor
Spanish
:
Pinacidilo
Descriptor
Portuguese
:
Pinacidil
Synonyms
English
:
Anhydrous, Pinacidil
Pinacidil Anhydrous
Pindac
Tree Number:
D02.078.370.729
Definition
English
:
A
guanidine
that opens
POTASSIUM CHANNELS
producing direct peripheral vasodilatation of the
ARTERIOLES
. It reduces
BLOOD PRESSURE
and peripheral resistance and produces fluid retention. (Martindale The Extra
Pharmacopoeia
, 31st ed)
Pharmacological Action:
Antihypertensive Agents
Vasodilator Agents
Membrane Transport Modulators
History Note
English
:
99; use PINACIDIL (NM) 1980-98
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
33787
Unique Identifier:
D020110
Occurrence in VHL
:
Similar:
DeCS