Search on: PIMOZIDE 
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Descriptor English:   Pimozide 
Descriptor Spanish:   Pimozida 
Descriptor Portuguese:   Pimozida 
Synonyms English:   Antalon
Orap
Orap forte
R-6238
R6238  
Tree Number:   D03.633.100.103.732
Definition English:   A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to HALOPERIDOL for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403) 
Pharmacological Action:   Antipsychotic Agents
Dopamine Antagonists
Anti-Dyskinesia Agents
 
History Note English:   73 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   11301 
Unique Identifier:   D010868 

Occurrence in VHL:
 

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