Search on: PEPSIN 
Descriptors Found: 1
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Descriptor English:   Pepsin A 
Descriptor Spanish:   Pepsina A 
Descriptor Portuguese:   Pepsina A 
Synonyms English:   Pepsin
Pepsin 1
Pepsin 3  
Tree Number:   D08.811.277.656.074.500.700
D08.811.277.656.300.048.700
Definition English:   Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice. 
Indexing Annotation English:   /biosyn /physiol permitted
Pharmacological Action:   Gastrointestinal Agents
 
History Note English:   91; was PEPSIN 1964-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   29296 
Unique Identifier:   D010434 

Occurrence in VHL:
 

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