Search on: PARAPROTEINS 
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Descriptor English:   Paraproteins 
Descriptor Spanish:   Paraproteínas 
Descriptor Portuguese:   Paraproteínas 
Tree Number:   D12.776.124.486.485.900
D12.776.124.790.651.900
D12.776.377.715.548.900
Definition English:   Abnormal immunoglobulins synthesized by atypical cells of the MONONUCLEAR PHAGOCYTE SYSTEM. Paraproteins containing only light chains lead to Bence Jones paraproteinemia, while the presence of only atypical heavy chains leads to heavy chain disease. Most of the paraproteins show themselves as an M-component (monoclonal gammopathy) in electrophoresis. Diclonal and polyclonal paraproteins are much less frequently encountered. 
Pharmacological Action:   Immunologic Factors
 
History Note English:   76; was see under GLOBULINS 1963-65 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   22253 
Unique Identifier:   D010266 

Occurrence in VHL:
 

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