Descriptors Found: 1
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Descriptor English:   Paralyses, Familial Periodic 
Descriptor Spanish:   Parálisis Periódicas Familiares 
Descriptor Portuguese:   Paralisias Periódicas Familiares 
Synonyms English:   Familial Periodic Paralyses
Familial Periodic Paralysis
Normokalemic Periodic Paralyses
Normokalemic Periodic Paralysis
Paralyses, Normokalemic Periodic
Paralysis, Familial Periodic
Paralysis, Normokalemic Periodic
Periodic Paralyses, Familial
Periodic Paralyses, Normokalemic
Periodic Paralysis, Familial
Periodic Paralysis, Normokalemic  
Tree Number:   C05.651.701
Definition English:   A heterogenous group of inherited disorders characterized by recurring attacks of rapidly progressive flaccid paralysis or myotonia. These conditions have in common a mutation of the gene encoding the alpha subunit of the sodium channel in skeletal muscle. They are frequently associated with fluctuations in serum potassium levels. Periodic paralysis may also occur as a non-familial process secondary to THYROTOXICOSIS and other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1481) 
Indexing Annotation English:   a specific disease entity: see MeSH definition
History Note English:   2000(1966) 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SU surgery TH therapy
UR urine VE veterinary
VI virology  
Record Number:   10434 
Unique Identifier:   D010245 

Occurrence in VHL: