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PANITUMUMAB
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DeCS
Descriptor
English
:
Panitumumab
Descriptor
Spanish
:
Panitumumab
Descriptor
Portuguese
:
Panitumumabe
Synonyms
English
:
ABX EGF Monoclonal Antibody
ABX-EGF MAb
ABX-EGF Monoclonal Antibody
Human Panitumumab Antibody
Monoclonal Antibody, ABX-EGF
Panitumumab Antibody, Human
Vectibix
Tree Number:
D12.776.124.486.485.114.224.060.864
D12.776.124.790.651.114.224.060.864
D12.776.377.715.548.114.224.200.864
Definition
English
:
Recombinant human monoclonal antibody that binds to and inhibits the function of the
EPIDERMAL GROWTH FACTOR
RECEPTOR. It is used in the treatment of EGFR-expressing metastatic colorectal cancer that expresses wild-type ras gene (see GENES, RAS).
Pharmacological Action:
Antineoplastic Agents, Immunological
History Note
English
:
2019 (2005)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
57669
Unique Identifier:
D000077544
Occurrence in VHL
:
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