Search on:
POMC
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Pro-Opiomelanocortin
Descriptor
Spanish
:
Proopiomelanocortina
Descriptor
Portuguese
:
Pró-Opiomelanocortina
Synonyms
English
:
ACTH Endorphin Precursor
ACTH beta Lipotropin Precursor
ACTH-Endorphin Precursor
ACTH-beta-Lipotropin Precursor
Corticotropin beta Lipotropin Precursor
Corticotropin-beta-Lipotropin Precursor
Endorphin ACTH Precursor
Endorphin-ACTH Precursor
Opiocortin
POMC
Pre POMC
Pre pro opiocortin
Pre-POMC
Pre-pro-opiocortin
Preproopiomelanocortin
Pro ACTH Endorphin
Pro Opio Melanocortin
Pro Opiocortin
Pro Opiomelanocortin
Pro-ACTH-Endorphin
Pro-Opio-Melanocortin
Pro-Opiocortin
Proopiocortin
Proopiomelanocortin
Tree Number:
D06.472.699.327.935
D06.472.699.631.525.600
D12.644.400.400.935
D12.644.548.365.935
D12.644.548.691.525.690
D12.776.631.650.405.935
D12.776.811.800
Definition
English
:
A 30-kDa protein synthesized primarily in the ANTERIOR
PITUITARY GLAND
and the
HYPOTHALAMUS
. It is also found in the skin and other peripheral
tissues
. Depending on species and
tissues
, POMC is cleaved by PROHORMONE CONVERTASES yielding various active
peptides
including ACTH;
BETA-LIPOTROPIN
;
ENDORPHINS
;
MELANOCYTE-STIMULATING HORMONES
; and others (GAMMA-LPH;
CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE
; N-terminal peptide of POMC or NPP).
History Note
English
:
1985
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
21050
Unique Identifier:
D011333
Occurrence in VHL
:
Similar:
DeCS