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DeCS
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Descriptor English:
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Proliferating Cell Nuclear Antigen
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Descriptor Spanish:
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Antígeno Nuclear de Célula en Proliferación
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Descriptor Portuguese:
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Antígeno Nuclear de Célula em Proliferação
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Synonyms English:
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Antigen, Proliferating Cell Nuclear
PCNA
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Tree Number:
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D12.776.660.740
D23.050.290.750
D23.101.140.600
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Definition English:
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Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during DNA replication. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types. |
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History Note English:
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95; was PROLIFERATING CELL NUCLEAR ANTIGEN (NM) 1983-94
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Allowable Qualifiers English:
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Record Number:
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32064
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Unique Identifier:
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D018809
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Occurrence in VHL:
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Similar:
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DeCS
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