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P-638
Descriptors Found:
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DeCS
Descriptor
English
:
Puromycin
Descriptor
Spanish
:
Puromicina
Descriptor
Portuguese
:
Puromicina
Synonyms
English
:
CL 13900
CL-13900
CL13900
P 638
P-638
P638
Puromycin Dihydrochloride
Puromycin Hydrochloride
Stylomycin
Tree Number:
D02.241.223.200.380
D03.633.100.759.590.138.711
D09.408.051.788
D13.570.583.138.711
Definition
English
:
A cinnamamido
ADENOSINE
found in
STREPTOMYCES
alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in
research
as an inhibitor of protein synthesis.
Pharmacological Action:
Antimetabolites, Antineoplastic
Protein Synthesis Inhibitors
Trypanocidal Agents
History Note
English
:
65(63)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
23434
Unique Identifier:
D011691
Occurrence in VHL
:
Similar:
DeCS