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OXOCHOLESTEROLS
Descriptors Found:
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DeCS
Descriptor
English
:
Ketocholesterols
Descriptor
Spanish
:
Cetocolesteroles
Descriptor
Portuguese
:
Cetocolesteróis
Synonyms
English
:
Oxocholesterols
Tree Number:
D04.210.500.247.222.265.450
D04.210.500.247.222.284.800.750
D04.210.500.247.808.197.800.750
D10.570.938.208.825.750
Definition
English
:
Cholesterol
substituted in any position by a keto moiety. The 7-keto isomer inhibits
cholesterol
uptake in the coronary
arteries
and aorta by blocking 3-hydroxy-3-methylglutaryl-CoA reductase activity.
History Note
English
:
91(80); was see under CHOLESTEROL 1980-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
7818
Unique Identifier:
D007653
Occurrence in VHL
:
Similar:
DeCS