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OSTEOPONTIN
Descriptors Found:
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DeCS
Descriptor
English
:
Osteopontin
Descriptor
Spanish
:
Osteopontina
Descriptor
Portuguese
:
Osteopontina
Synonyms
English
:
Bone Sialoprotein 1
Bone Sialoprotein I
Secreted Phosphoprotein 1
Sialoprotein 1
Sialoprotein 1, Bone
Sialoprotein I, Bone
Uropontin
Tree Number:
D12.644.276.374.625
D12.776.395.700.837
D12.776.467.374.625
D12.776.860.300.762
D23.529.374.625
Definition
English
:
A negatively-charged
extracellular matrix
protein that plays a role in the regulation of BONE
metabolism
and a variety of other biological functions. Cell signaling by
osteopontin
may occur through a
cell adhesion
sequence that recognizes INTEGRIN ALPHA-V BETA-3.
History Note
English
:
2007(1987)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52284
Unique Identifier:
D053495
Occurrence in VHL
:
Similar:
DeCS