Search on: NOMIFENSINE 
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Descriptor English:   Nomifensine 
Descriptor Spanish:   Nomifensina 
Descriptor Portuguese:   Nomifensina 
Synonyms English:   Hoe 984
Hoe-984
Hoe984
Linamiphen
Maleate, Nomifensine
Merital
Nomifensin
Nomifensine Maleate
Nomifensine Maleate (1:1)  
Tree Number:   D03.633.100.531.535
Definition English:   An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266) 
Pharmacological Action:   Dopamine Uptake Inhibitors
 
History Note English:   86(78); was see under ISOQUINOLINES 1978-85 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   24345 
Unique Identifier:   D009627 

Occurrence in VHL:
 

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