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NOGALAMYCIN
Descriptors Found:
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DeCS
Descriptor
English
:
Nogalamycin
Descriptor
Spanish
:
Nogalamicina
Descriptor
Portuguese
:
Nogalamicina
Synonyms
English
:
U 15167
U-15167
U15167
Tree Number:
D02.455.426.559.847.562.050.200.650
D04.615.562.050.200.650
D09.408.051.059.200.650
Definition
English
:
An anthrocycline from a
Streptomyces
nogalater variant. It is a cytolytic antineoplastic that inhibits DNA-dependent RNA synthesis by binding to DNA.
Pharmacological Action:
Antibiotics, Antineoplastic
Intercalating Agents
Nucleic Acid Synthesis Inhibitors
History Note
English
:
91(76); was see under DAUNORUBICIN 1981-90; was see under NAPHTHACENES 1976-80
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
24270
Unique Identifier:
D009621
Occurrence in VHL
:
Similar:
DeCS