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DeCS
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Descriptor English:
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Necroptosis
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Descriptor Spanish:
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Necroptosis
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Descriptor Portuguese:
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Necroptose
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Tree Number:
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G04.146.954.500
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Definition English:
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A form of regulated cell death initiated by perturbations of extracellular or intracellular homeostasis that trigger a specific cell death pathway involving the activation of RIPK3 and MLKL (mixed lineage kinase domain like pseudokinase). Morphological changes include cytoplasmic and organellar swelling, rupture of the PLASMA MEMBRANE, and CHROMATIN CONDENSATION. |
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Indexing Annotation English:
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do not confuse with NECROSIS the pathological process
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History Note English:
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2020
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Allowable Qualifiers English:
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Record Number:
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59170
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Unique Identifier:
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D000079302
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Occurrence in VHL:
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Similar:
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DeCS
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