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DeCS
Descriptor
English
:
Suramin
Descriptor
Spanish
:
Suramina
Descriptor
Portuguese
:
Suramina
Synonyms
English
:
Germanin
Hexasodium Salt Suramin
Monosodium Salt Suramin
Moranil
Naganin
Naganol
Naphuride
Salt Suramin, Hexasodium
Salt Suramin, Monosodium
Sodium, Suramin
Suramin Sodium
Suramin, Hexasodium Salt
Suramin, Monosodium Salt
Tree Number:
D02.455.426.559.847.638.555.750
D02.886.645.600.080.050.650.750
D04.615.638.555.750
Definition
English
:
A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African
trypanosomiasis
and it has been used clinically with
diethylcarbamazine
to kill the adult
Onchocerca
. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
Pharmacological Action:
Antinematodal Agents
Antineoplastic Agents
Trypanocidal Agents
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
13879
Unique Identifier:
D013498
Occurrence in VHL
:
Similar:
DeCS