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DeCS
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Descriptor English:
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Leflunomide
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Descriptor Spanish:
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Leflunamida
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Descriptor Portuguese:
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Leflunomida
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Synonyms English:
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Arava
HWA 486
HWA-486
HWA486
N-(4-Trifluoromethyphenyl)-5-methylisoxazole-4-carboxamide
SU101
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Tree Number:
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D03.383.129.385.475
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Definition English:
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An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS. |
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Pharmacological Action:
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Enzyme Inhibitors
Immunosuppressive Agents
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History Note English:
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2019 (1985)
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Allowable Qualifiers English:
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Record Number:
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57623
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Unique Identifier:
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D000077339
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Occurrence in VHL:
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Similar:
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DeCS
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