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MUSCIMOL
Descriptors Found:
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DeCS
Descriptor
English
:
Muscimol
Descriptor
Spanish
:
Muscimol
Descriptor
Portuguese
:
Muscimol
Synonyms
English
:
Agarin
Pantherine
Tree Number:
D03.383.129.462.470
D23.946.587.587
Definition
English
:
A neurotoxic isoxazole isolated from species of
AMANITA
. It is obtained by
decarboxylation
of
IBOTENIC ACID
.
Muscimol
is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and
tissue
studies.
Pharmacological Action:
GABA-A Receptor Agonists
See Related
English
:
Receptors, GABA-A
History Note
English
:
86(79); was see under OXAZOLES 1979-85
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
9308
Unique Identifier:
D009118
Occurrence in VHL
:
Similar:
DeCS