|
1 / 1
|
DeCS
|
|
 |
|
Descriptor English:
|
|
MicroRNAs
|
|
Descriptor Spanish:
|
|
MicroARNs
|
|
Descriptor Portuguese:
|
|
MicroRNAs
|
|
Synonyms English:
|
|
Micro RNA
MicroRNA
MicroRNA, Primary
Primary MicroRNA
Primary miRNA
RNA, Micro
RNA, Small Temporal
Small Temporal RNA
Temporal RNA, Small
miRNA
miRNA, Primary
miRNAs
pre miRNA
pre-miRNA
pri miRNA
pri-miRNA
stRNA
|
|
Tree Number:
|
|
D13.150.650.319
D13.444.735.150.319
D13.444.735.790.552.500
|
|
Definition English:
|
|
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing. |
|
See Related English:
|
|
RNA, Small Interfering
|
|
History Note English:
|
|
2003; use MICRORNAS (NM) 2001-2002
|
|
Allowable Qualifiers English:
|
|
|
|
Record Number:
|
|
37535
|
|
Unique Identifier:
|
|
D035683
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS
|
|