Search on: MELANOCORTINS 
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Descriptor English:   Melanocortins 
Descriptor Spanish:   Melanocortinas 
Descriptor Portuguese:   Melanocortinas 
Tree Number:   D06.472.699.327.935.531
D06.472.699.631.525.600.531
D12.644.400.400.935.531
D12.644.548.365.935.531
D12.644.548.691.525.690.531
D12.776.631.650.405.935.531
Definition English:   Peptides derived from pro-opiomelanocortin (POMC) which can stimulate MELANOCYTES or CORTICOTROPHS. Melanocortins include ACTH; ALPHA-MSH; and other peptides such as BETA-MSH and GAMMA-MSH, derived from other fragments of POMC. These peptides act through a variety of MELANOCORTIN RECEPTORS to control different functions including steroidogenesis, energy homeostasis, feeding, and skin pigmentation. 
History Note English:   2007 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52211 
Unique Identifier:   D053486 

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