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Descriptor English:   Melanocyte-Stimulating Hormones 
Descriptor Spanish:   Hormonas Estimuladoras de los Melanocitos 
Descriptor Portuguese:   Hormônios Estimuladores de Melanócitos 
Synonyms English:   MSH
MSH (Melanocyte-Stimulating Hormones)
Melanocyte Stimulating Hormones
Melanophore Stimulating Hormone
Melanophore-Stimulating Hormone
Melanotropin  
Tree Number:   D06.472.699.327.935.531.750
D06.472.699.631.525.600.531.750
D12.644.400.400.935.531.750
D12.644.400.460
D12.644.548.365.935.531.750
D12.644.548.691.525.690.531.750
D12.776.631.650.405.935.531.750
D12.776.631.650.460
Definition English:   Peptides with the ability to stimulate pigmented cells MELANOCYTES in mammals and MELANOPHORES in lower vertebrates. By stimulating the synthesis and distribution of MELANIN in these pigmented cells, they increase coloration of skin and other tissue. MSHs, derived from pro-opiomelanocortin (POMC), are produced by MELANOTROPHS in the INTERMEDIATE LOBE OF PITUITARY; CORTICOTROPHS in the ANTERIOR LOBE OF PITUITARY, and the hypothalamic neurons in the ARCUATE NUCLEUS OF HYPOTHALAMUS. 
Pharmacological Action:   Hormones
 
History Note English:   2006(1963) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   23523 
Unique Identifier:   D009074 

Occurrence in VHL:
 

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