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DeCS
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Descriptor English:
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Monoamine Oxidase
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Descriptor Spanish:
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Monoaminooxidasa
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Descriptor Portuguese:
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Monoaminoxidase
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Synonyms English:
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Amine Oxidase (Flavin-Containing)
MAO
MAO A
MAO B
MAO-A
MAO-B
Monoamine Oxidase A
Monoamine Oxidase B
Oxidase, Monoamine
Oxidase, Tyramine
Type A Monoamine Oxidase
Type B Monoamine Oxidase
Tyramine Oxidase
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Tree Number:
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D08.811.682.664.750
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Definition English:
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An enzyme that catalyzes the oxidative deamination of naturally occurring monoamines. It is a flavin-containing enzyme that is localized in mitochondrial membranes, whether in nerve terminals, the liver, or other organs. Monoamine oxidase is important in regulating the metabolic degradation of catecholamines and serotonin in neural or target tissues. Hepatic monoamine oxidase has a crucial defensive role in inactivating circulating monoamines or those, such as tyramine, that originate in the gut and are absorbed into the portal circulation. (From Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 8th ed, p415) EC 1.4.3.4. |
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Entry Combination - descr/qualif English:
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Monoamine Oxidase/antagonists & inhibitors use Monoamine Oxidase Inhibitors
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History Note English:
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63; for TYRAMINE OXIDASE use MONOAMINE OXIDASE (NM) 1980-98
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Allowable Qualifiers English:
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Record Number:
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9187
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Unique Identifier:
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D008995
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Occurrence in VHL:
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Similar:
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DeCS
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