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LYMPHOTOXIN-ALPHA
Descriptors Found:
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DeCS
Descriptor
English
:
Lymphotoxin-alpha
Descriptor
Spanish
:
Linfotoxina-alfa
Descriptor
Portuguese
:
Linfotoxina-alfa
Synonyms
English
:
Lymphotoxin
Lymphotoxin alpha
Lymphotoxin alpha3
Lymphotoxin-alpha, Soluble
Lymphotoxin-alpha3
Soluble Lymphotoxin alpha
Soluble Lymphotoxin-alpha
TNF Superfamily, Member 1
TNF-beta
Tumor Necrosis Factor Ligand Superfamily Member 1
Tumor Necrosis Factor beta
Tumor Necrosis Factor-beta
alpha Lymphotoxin
alpha-Lymphotoxin
Tree Number:
D12.644.276.374.480.438
D12.644.276.374.750.500
D12.776.467.374.480.438
D12.776.467.374.750.500
D23.529.374.480.438
D23.529.374.750.500
Definition
English
:
A tumor
necrosis
factor
family
member that is released by activated
LYMPHOCYTES
. Soluble lymphotoxin is specific for TUMOR
NECROSIS
FACTOR RECEPTOR TYPE I; TUMOR
NECROSIS
FACTOR RECEPTOR TYPE II; and TUMOR
NECROSIS
FACTOR RECEPTOR SUPERFAMILY, MEMBER 14.
Lymphotoxin-alpha
can form a membrane-bound heterodimer with
LYMPHOTOXIN-BETA
that has specificity for the
LYMPHOTOXIN BETA RECEPTOR.
Indexing Annotation
English
:
for "lymphocytotoxin" use
CYTOTOXINS
and
LYMPHOCYTES
History Note
English
:
2007 (1974-1977); for TUMOR NECROSIS FACTOR-BETA & TNF-BETA use TUMOR NECROSIS FACTOR 1988-1989
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
29490
Unique Identifier:
D008233
Occurrence in VHL
:
Similar:
DeCS