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LACTOFERRIN
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DeCS
Descriptor
English
:
Lactoferrin
Descriptor
Spanish
:
Lactoferrina
Descriptor
Portuguese
:
Lactoferrina
Synonyms
English
:
Lactotransferrin
Tree Number:
D08.811.277.656.300.760.471
D08.811.277.656.959.350.471
D12.776.157.427.750.249
D12.776.256.159.750.816.500.507
D12.776.377.457.507
D12.776.395.507
D12.776.556.579.750.249
Definition
English
:
An iron-binding protein that was originally characterized as a milk protein. It is widely distributed in secretory fluids and is found in the neutrophilic granules of
LEUKOCYTES
. The N-terminal part of
lactoferrin
possesses a
serine
protease which functions to inactivate the TYPE III SECRETION SYSTEM used by
bacteria
to export
virulence
proteins
for host cell invasion.
Pharmacological Action:
Anti-Infective Agents
History Note
English
:
91(73); was see under LACTOGLOBULINS 1973-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
7958
Unique Identifier:
D007781
Occurrence in VHL
:
Similar:
DeCS