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DeCS
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Descriptor English:
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Sulindac
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Descriptor Spanish:
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Sulindac
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Descriptor Portuguese:
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Sulindaco
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Synonyms English:
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Aclin
Apo Sulin
Apo-Sulin
Arthrobid
Arthrocine
Chibret
Clinoril
Copal
Kenalin
Klinoril
MK 231
MK-231
MK231
Novo Sundac
Novo-Sundac
Nu Sulindac
Nu-Sulindac
Sulindal
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Tree Number:
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D02.455.426.559.847.486.875
D04.615.486.875
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Definition English:
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A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects. |
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Pharmacological Action:
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Anti-Inflammatory Agents, Non-Steroidal
Antineoplastic Agents
Cyclooxygenase Inhibitors
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History Note English:
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90(79); was see under INDENES 1979-89
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Allowable Qualifiers English:
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Record Number:
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27862
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Unique Identifier:
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D013467
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Occurrence in VHL:
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Similar:
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DeCS
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