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KARYOPHERINS
Descriptors Found:
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DeCS
Descriptor
English
:
Karyopherins
Descriptor
Spanish
:
Carioferinas
Descriptor
Portuguese
:
Carioferinas
Synonyms
English
:
Exportins
Importin
Importins
Transportin
Transportins
Tree Number:
D12.776.157.530.750.500
D12.776.543.585.750.500
D12.776.660.502
Definition
English
:
A
family
of
proteins
involved in NUCLEOCYTOPLASMIC TRANSPORT.
Karyopherins
are heteromeric molecules composed two major types of components,
ALPHA KARYOPHERINS
and
BETA KARYOPHERINS
, that function together to transport molecules through the
NUCLEAR PORE
COMPLEX. Several other
proteins
such as RAN GTP BINDING PROTEIN and
CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN
bind to
karyopherins
and participate in the transport process.
See Related
English
:
Active Transport, Cell Nucleus
History Note
English
:
2002; use KARYOPHERINS (NM) 1995-2001
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
36191
Unique Identifier:
D028884
Occurrence in VHL
:
Similar:
DeCS