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IONOPHORES
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DeCS
Descriptor
English
:
Ionophores
Descriptor
Spanish
:
Ionóforos
Descriptor
Portuguese
:
Ionóforos
Tree Number:
D27.505.519.562.374
D27.720.395
Definition
English
:
Chemical agents that increase the
permeability
of biological or artificial lipid
membranes
to specific ions. Most
ionophores
are relatively small organic molecules that act as mobile carriers within
membranes
or coalesce to form ion permeable channels across
membranes
. Many are antibiotics, and many act as
uncoupling agents
by short-circuiting the proton
gradient
across
mitochondrial membranes.
See Related
English
:
Cell Membrane Permeability
History Note
English
:
76
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
7644
Unique Identifier:
D007476
Occurrence in VHL
:
Similar:
DeCS