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INFLAMMASOMES
Descriptors Found:
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DeCS
Descriptor
English
:
Inflammasomes
Descriptor
Spanish
:
Inflamasomas
Descriptor
Portuguese
:
Inflamassomos
Synonyms
English
:
Inflammasome
Pyroptosome
Pyroptosomes
Tree Number:
D05.500.224
Definition
English
:
Multiprotein complexes
that mediate the activation of CASPASE-1. Dysregulation of
inflammasomes
has also been linked to a number of autoinflammatory and autoimmune disorders.
See Related
English
:
Immunity, Innate
Inflammation Mediators
NLR Family, Pyrin Domain-Containing 3 Protein
History Note
English
:
2011
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
54035
Unique Identifier:
D058847
Occurrence in VHL
:
Similar:
DeCS