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Descriptor English:   Immunoglobulin M 
Descriptor Spanish:   Inmunoglobulina M 
Descriptor Portuguese:   Imunoglobulina M 
Synonyms English:   19S Gamma Globulin
Gamma Globulin, 19S
IgM
IgM1
IgM2  
Tree Number:   D12.776.124.486.485.114.619.574
D12.776.124.790.651.114.619.574
D12.776.377.715.548.114.619.574
Definition English:   A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally being called a macroglobulin. 
Indexing Annotation English:   /defic = IMMUNOGLOBULIN M / defic + DYSGAMMAGLOBULINEMIA (IM); gammopathy: coordinate IMMUNOGLOBULIN M (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA (IM), follow text;
Pharmacological Action:   Immunologic Factors
 
See Related English:   Immunoglobulin J-Chains
 
History Note English:   2002(1973) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PD pharmacology PH physiology
PO poisoning RE radiation effects
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   22207 
Unique Identifier:   D007075 

Occurrence in VHL:
 

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