Search on: ISCOMS 
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Descriptor English:   ISCOMs 
Descriptor Spanish:   ISCOMs 
Descriptor Portuguese:   ISCOMs 
Synonyms English:   Complexes, Immuno-Stimulating
Complexes, Immunostimulating
ISCOM
Immuno Stimulating Complexes
Immuno-Stimulating Complexes
Immunostimulating Complexes  
Tree Number:   D20.215.894.860.449
Definition English:   A formulation for presenting an antigen to induce specific immunologic responses. It consists of an assembly of antigens in multimeric form. The assembly is attached to a matrix with a built-in adjuvant, saponin. ISCOMs induce strong serum antibody responses, and are used as highly immunogenic forms of subunit vaccines. 
Indexing Annotation English:   coord IM with specific type of vaccine (IM or NIM); DF: ISCOM
Pharmacological Action:   Adjuvants, Immunologic
 
See Related English:   Saponins
 
History Note English:   92 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PD pharmacology
PO poisoning RE radiation effects
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30027 
Unique Identifier:   D016882 

Occurrence in VHL:
 

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