Search on: IL-10 
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Descriptor English:   Interleukin-10 
Descriptor Spanish:   Interleucina-10 
Descriptor Portuguese:   Interleucina-10 
Synonyms English:   CSIF-10
Cytokine Synthesis Inhibitory Factor
IL-10
IL10
Interleukin 10  
Tree Number:   D12.644.276.374.465.510
D12.776.467.374.465.510
D23.529.374.465.510
Definition English:   A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein. 
History Note English:   92; was INTERLEUKIN-10 (NM) 1990-91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   30030 
Unique Identifier:   D016753 

Occurrence in VHL:
 

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