Search on: IL-1 
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Descriptor English:   Interleukin-1 
Descriptor Spanish:   Interleucina-1 
Descriptor Portuguese:   Interleucina-1 
Synonyms English:   Epidermal Cell Derived Thymocyte Activating Factor
Epidermal Cell Derived Thymocyte-Activating Factor
IL-1
Interleukin 1
Interleukin I
Lymphocyte Activating Factor
Lymphocyte-Activating Factor
Macrophage Cell Factor
T Helper Factor  
Tree Number:   D12.644.276.374.465.010
D12.644.276.374.500.400
D12.776.467.374.465.010
D12.776.467.374.500.400
D23.529.374.465.131
D23.529.374.500.400
Definition English:   A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation. 
See Related English:   Receptors, Interleukin-1
 
History Note English:   1990(1983) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   29487 
Unique Identifier:   D007375 

Occurrence in VHL:
 

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