Search on: IGF-II 
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Descriptor English:   Insulin-Like Growth Factor II 
Descriptor Spanish:   Factor II del Crecimiento Similar a la Insulina 
Descriptor Portuguese:   Fator de Crescimento Insulin-Like II 
Synonyms English:   Factor, Multiplication-Stimulating
IGF-2
IGF-II
Insulin Like Growth Factor II
Insulin Like Somatomedin Peptide II
Insulin-Like Somatomedin Peptide II
Multiplication Stimulating Activity
Multiplication Stimulating Factor
Multiplication-Stimulating Activity
Multiplication-Stimulating Factor
Somatomedin A
Somatomedin MSA  
Tree Number:   D12.644.276.937.420
D12.776.124.862.425
D12.776.467.937.420
D23.529.937.420
Definition English:   A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BLOOD. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal growth factor in contrast to INSULIN-LIKE GROWTH FACTOR I, which is a major growth factor in adults. 
See Related English:   Receptor, IGF Type 1
Receptor, IGF Type 2
 
History Note English:   1991(1986) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   22313 
Unique Identifier:   D007335 

Occurrence in VHL:
 

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