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GALACTOCEREBROSIDES
Descriptors Found:
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DeCS
Descriptor
English
:
Galactosylceramides
Descriptor
Spanish
:
Galactosilceramidas
Descriptor
Portuguese
:
Galactosilceramidas
Synonyms
English
:
Ceramides, Galactosyl
Galactocerebrosides
Galactosyl Ceramides
Tree Number:
D02.065.313.250.450
D09.400.410.420.525.200.250.450
D10.390.470.675.200.250.450
D10.570.877.360.612.200.250.450
Definition
English
:
Cerebrosides
which contain as their polar head group a
galactose
moiety bound in glycosidic linkage to the hydroxyl group of ceramide. Their accumulation in
tissue
, due to a defect in
beta-galactosidase
, is the cause of galactosylceramide lipidosis or globoid cell leukodystrophy.
History Note
English
:
91(79); was see under CEREBROSIDES 1979-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
5837
Unique Identifier:
D005699
Occurrence in VHL
:
Similar:
DeCS