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FIRDAPSE
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DeCS
Descriptor
English
:
Amifampridine
Descriptor
Spanish
:
Amifampridina
Descriptor
Portuguese
:
Amifampridina
Synonyms
English
:
3,4 Diaminopyridine
3,4-Diaminopyridine
Amifampridine Phosphate
Firdapse
Ruzurgi
Tree Number:
D02.092.080.060.500
D03.383.725.050.060.500
Definition
English
:
4-Aminopyridine
derivative that acts as a
POTASSIUM
CHANNEL blocker to increase release of
ACETYLCHOLINE
from nerve terminals. It is used in the treatment of CONGENITAL MYASTHENIC SYNDROMES.
Pharmacological Action:
Neuromuscular Agents
Potassium Channel Blockers
History Note
English
:
2019 (1978)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
57749
Unique Identifier:
D000077770
Occurrence in VHL
:
Similar:
DeCS