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DeCS
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Descriptor English:
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Filamins
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Descriptor Spanish:
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Filaminas
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Descriptor Portuguese:
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Filaminas
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Synonyms English:
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1-Like Protein, Filamin
1-Like Proteins, Filamin
280 kDa Actin Binding Protein
280 kDa Actin-Binding Protein
Cs, Filamin
Filamin
Filamin 1
Filamin 1 Like Protein
Filamin 1-Like Protein
Filamin 1-Like Proteins
Filamin A
Filamin B
Filamin C
Filamin Cs
Merofilamin
Merofilamins
Protein, Filamin 1-Like
Proteins, Filamin 1-Like
alpha Filamin
alpha-Filamin
alpha-Filamins
beta Filamin
beta-Filamin
beta-Filamins
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Tree Number:
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A11.284.430.214.190.750.050.414
D05.750.078.730.315
D12.776.210.249
D12.776.220.525.315
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Definition English:
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A family of crosslinking filament proteins encoded by distinct FLN genes. Filamins are involved in cell adhesion, spreading, and migration, acting as scaffolds for over 90 binding partners including channels, receptors, intracellular signaling molecules and transcription factors. Due to the range of molecular interactions, mutations in FLN genes result in anomalies with moderate to lethal consequences. |
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History Note English:
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2014
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Allowable Qualifiers English:
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Record Number:
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55183
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Unique Identifier:
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D064448
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Occurrence in VHL:
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Similar:
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DeCS
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