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DeCS
Descriptor
English
:
Panobinostat
Descriptor
Spanish
:
Panobinostat
Descriptor
Portuguese
:
Panobinostat
Synonyms
English
:
Farydak
LBH 589
LBH589
NVP LBH589
NVP-LBH589
Tree Number:
D02.092.570.394.535
D02.241.511.372.535
D03.633.100.473.746
Definition
English
:
An indole and hydroxamic acid derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used as an antineoplastic agent in combination with
BORTEZOMIB
and
DEXAMETHASONE
for the treatment of
MULTIPLE MYELOMA.
Pharmacological Action:
Antineoplastic Agents
Histone Deacetylase Inhibitors
History Note
English
:
2019 (2005)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
57746
Unique Identifier:
D000077767
Occurrence in VHL
:
Similar:
DeCS