Descriptors Found: 1
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Descriptor English:   Kleine-Levin Syndrome 
Descriptor Spanish:   Síndrome de Kleine-Levin 
Descriptor Portuguese:   Síndrome de Kleine-Levin 
Synonyms English:   Familial Hibernation (Kleine-Levin) Syndrome
Familial Kleine Levin Syndrome
Familial Kleine-Levin Syndrome
Hibernation Syndrome, Kleine-Levin
Hypersomnia, Periodic
Kleine Levin Critchley Syndrome
Kleine Levin Hibernation Syndrome
Kleine Levin Syndrome
Kleine-Levin Hibernation Syndrome
Kleine-Levin Syndrome, Familial
Kleine-Levin-Critchley Syndrome
Periodic Hypersomnia
Periodic Hypersomnias
Syndrome, Familial Kleine-Levin
Syndrome, Kleine-Levin
Syndrome, Kleine-Levin Hibernation
Syndrome, Kleine-Levin-Critchley  
Tree Number:   C10.886.425.800.200.500
Definition English:   A rare condition characterized by recurrent hypersomnias associated with hyperphagia, occurring primarily in males in the second to third decade of life. Clinical features include mental confusion, excessive sleep requirements (approximately 18 hours per day), restlessness, and in some cases hallucinations. Episodes have a duration of days to weeks, and may recur several times per year. This condition may resolve spontaneously over several years. (From Adams, et al., Principles of Neurology, 6th ed, p569) 
History Note English:   94 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SU surgery TH therapy
UR urine VE veterinary
VI virology  
Record Number:   31370 
Unique Identifier:   D017593 

Occurrence in VHL: