Descriptors Found: 1
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Descriptor English:   Complement C3b Inactivator Proteins 
Descriptor Spanish:   Proteínas Inactivadoras del Complemento C3b 
Descriptor Portuguese:   Proteínas Inativadoras do Complemento C3b 
Synonyms English:   C3b Inactivators
C3b Inhibitors
Complement 3b Inactivators
Complement 3b Inhibitors
Complement C3b Inactivators
Complement C3b Inhibitor Proteins
Conglutinogen Activating Factors
Factors, Conglutinogen Activating
Inactivators, C3b
Inactivators, Complement 3b
Inactivators, Complement C3b
Inhibitors, C3b
Inhibitors, Complement 3b  
Tree Number:   D12.776.124.486.274.920.325
Definition English:   Endogenous proteins that inhibit or inactivate COMPLEMENT C3B. They include COMPLEMENT FACTOR H and COMPLEMENT FACTOR I (C3b/C4b inactivator). They cleave or promote the cleavage of C3b into inactive fragments, and thus are important in the down-regulation of COMPLEMENT ACTIVATION and its cytolytic sequence. 
Pharmacological Action:   Complement Inactivating Agents
History Note English:   2006 (1978) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   22142 
Unique Identifier:   D003180 

Occurrence in VHL: