Descriptors Found: 1
Displaying: 1 .. 1  

 1 / 1 DeCS     
Descriptor English:   1-Alkyl-2-acetylglycerophosphocholine Esterase 
Descriptor Spanish:   1-Alquil-2-acetilglicerofosfocolina Esterasa 
Descriptor Portuguese:   1-Alquil-2-acetilglicerofosfocolina Esterase 
Synonyms English:   1 Alkyl 2 acetylglycerophosphocholine Esterase
2-Acetylhydrolase, PAF
Acetylhydrolase II, PAF
Acetylhydrolase, PAF
Esterase, 1-Alkyl-2-acetylglycerophosphocholine
Factor Hydrolase, Platelet-Activating
Hydrolase, Platelet-Activating Factor
Lipoprotein Associated Phospholipase A2
Lipoprotein-Associated Phospholipase A(2)
Lipoprotein-Associated Phospholipase A2
PAF 2 Acetylhydrolase
PAF 2 Acylhydrolase
PAF 2-Acetylhydrolase
PAF 2-Acylhydrolase
PAF Acetylhydrolase
PAF Acetylhydrolase II
Phospholipase A2, Lipoprotein-Associated
Platelet Activating Factor Hydrolase
Platelet activating Factor Acetylhydrolase IB
Platelet-Activating Factor Hydrolase
Platelet-activating Factor Acetylhydrolase IB  
Tree Number:   D08.811.277.352.100.680.750.937.249
Definition English:   A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA. 
Indexing Annotation English:   /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS
History Note English:   2004(1983) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   38141 
Unique Identifier:   D043203 

Occurrence in VHL: