Search on: FKBP12 
Descriptors Found: 1
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Descriptor English:   Tacrolimus Binding Protein 1A 
Descriptor Spanish:   Proteína 1A de Unión a Tacrolimus 
Descriptor Portuguese:   Proteína 1A de Ligação a Tacrolimo 
Synonyms English:   FK506 Binding Protein 1
FK506 Binding Protein 1A
FK506-Binding Protein 1
FK506-Binding Protein 1A
FKBP 12
FKBP-12
FKBP12
Macrophilin 12
Macrophilin-12  
Tree Number:   D08.811.399.325.500.400.700.500
D12.776.543.750.705.400.700.500
D12.776.827.275.700.500
Definition English:   A 12-KDa tacrolimus binding protein that is found associated with and may modulate the function of calcium release channels. It is a peptidyl-prolyl cis/trans isomerase which is inhibited by both tacrolimus (commonly called FK506) and SIROLIMUS. 
History Note English:   2001; use TACROLIMUS BINDING PROTEINS (NM) 1991-2000 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   35327 
Unique Identifier:   D022061 

Occurrence in VHL:
 

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