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FC1157A
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DeCS
Descriptor
English
:
Toremifene
Descriptor
Spanish
:
Toremifeno
Descriptor
Portuguese
:
Toremifeno
Synonyms
English
:
Citrate, Toremifene
FC 1157a
FC-1157a
FC1157a
Fareston
Toremifene Citrate
Toremifene Citrate (1:1)
Toremifene, (E)-Isomer
Tree Number:
D02.455.426.559.389.150.700.900.900
Definition
English
:
A first generation selective estrogen receptor modulator (SERM). Like
TAMOXIFEN
, it is an estrogen agonist for bone
tissue
and
cholesterol
metabolism
but is antagonistic on mammary and uterine
tissue.
Pharmacological Action:
Antineoplastic Agents, Hormonal
Selective Estrogen Receptor Modulators
Bone Density Conservation Agents
History Note
English
:
93; was TOREMIFENE (NM) 1985-92
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
30475
Unique Identifier:
D017312
Occurrence in VHL
:
Similar:
DeCS